| Trans Num | Date | Details |
| 2016.41 | 2016-12-22 | Detroit trades Chris Owings, Cory Spangenberg, Dallas Keuchel, Chad Bettis, and Jake Thompson to Philadelphia for Cole Hamels and David Ross. |
| 2016.39 | 2016-11-29 | Toronto trades Chad Bettis and Chris Owings to Detroit for C.C. Sabathia and Steven Moya. |