| Trans Num | Date | Details |
| 2012.19 | 2012-03-01 | Pittsburgh trades Reid Brignac to Kansas City for KCR 2013 #5 and KCR 2013 #6. |
| 2010.17 | 2010-08-01 | Pittsburgh trades Drew Stubbs, Akinori Iwamura, and DJ Carrasco to Tampa Bay for Reid Brignac, Andy Sonnanstine, and Robert Manuel. |