| Trans Num | Date | Details |
| 2025.3 | 2025-01-04 | Cleveland Indians trade Jose Siri and Mitch Keller to the Pittsburgh Pirates for Jameson Taillon and Rowdy Tellez. |
| 2020.25 | 2020-08-06 | Cleveland Indians trade Justin Verlander to the Pittsburgh Pirates for Mitch Keller. |