| Trans Num | Date | Details |
| 2017.16 | 2017-01-25 | Kansas City trades Colby Rasmus to Toronto for Francisco Liriano. |
| 2016.46 | 2016-12-28 | Pittsburgh trades Francisco Liriano to Toronto for Drew Hutchison and Sammy Solis. |
| 2012.49 | 2012-12-21 | Pittsburgh trades Jeff Karstens and Chris Resop to Minnesota for Francisco Liriano. |