| Trans Num | Date | Details |
| 2026.11 | 2026-02-12 | Milwaukee Brewers trade MIL 2027 #3 to the Pittsburgh Pirates for Reese McGuire. |
| 2025.2 | 2025-01-03 | Toronto Blue Jays trade Reese McGuire and Spencer Horwitz to the Pittsburgh Pirates for Aroldis Chapman, Jesus Sanchez, and Jo Adell. |