| Trans Num | Date | Details |
| 2016.41 | 2016-12-22 | Detroit trades Chris Owings, Cory Spangenberg, Dallas Keuchel, Chad Bettis, and Jake Thompson to Philadelphia for Cole Hamels and David Ross. |
| 2015.27 | 2015-06-23 | Pittsburgh trades Jason Castro, J.J. Hoover, Cory Spangenberg, and Carlos Quentin to Detroit for Steve Pearce, Michael Saunders, Gavin Floyd, and Chris Gimenez. |