| Trans Num | Date | Details |
| 2021.23 | 2021-08-31 | Pittsburgh Pirates trade Carlos Carrasco, Will Harris, Anthony Rendon, Matt Wieters, and PIT 2022 #4 to the Arizona Diamondbacks for Sam Howard, Luis Patino, Pavin Smith, and Daulton Varsho. |
| 2020.28 | 2020-08-17 | Pittsburgh Pirates trade A.J. Cole and Zack Collins to the Baltimore Orioles for Sam Dyson and Matt Wieters. |